If you're dealing with new clients or coworkers at the beginning of the week, make sure that you're attuned to whatever sensitivities they bring to the table. It's never a good time to put your foot in your mouth. On wednesday and thursday, a big opportunity may come knocking, but it might also involve prioritizing career over family or a relationship. Think long and hard, and talk to someone who helps you get grounded. Work on friday and saturday doesn't involve such difficult choices. In fact, it's a breeze. Sunday, however, is meant more for some rest and relaxation than for business matters.